Colorful DNA sculpture inside Valencia's science complex, showcasing modern architecture and art.

What is SRSF1 (or Serine/Arginine-Rich Splicing Factor 1)?

SRSF1 is a protein that helps cells edit RNA before using it to make proteins. Its best-known job is RNA splicing, the process that removes unneeded sections from a new RNA copy and joins the useful pieces together. By helping decide which pieces stay and which go, SRSF1 can change the final instructions a gene sends to the cell. Scientists have also linked SRSF1 to cancer, development, fertility, liver health, blood-vessel growth, and, more recently, aging.

A hand holding a large piece of clear ice against a light background.

Human Fingerprints on Climate Are Clearer Now

Five climate scientists reviewed three decades of fingerprint research and say rainfall, ocean, snow and stratosphere records now point the same way, while conceding that attributing individual extreme events remains hard.

A frustrated man in a red shirt holds his head in stress against a neutral background.

Lose the AI Helper and Many People Stop Trying

Three randomized online experiments with 1,222 participants found that people who lost a chatbot’s help solved fewer fraction and reading problems than people who never had it. Direct-answer users fared worst, though that comparison was not randomized.

Close-up of a man holding his tattooed back outdoors, possibly experiencing back pain.

Your Brain Takes Back Pain Personally

Adults with chronic low back pain showed higher blood flow in two midline brain regions during a flare-provoking leg raise, but the study had no pain-free comparison group and tested no treatment.