Aging is dedicated to advancing our understanding of the biological mechanisms that drive aging and the development of age-related diseases. Our mission is to serve as a platform for high-quality research that uncovers the cellular, molecular, and systemic processes underlying aging, and translates these insights into strategies to extend healthspan and delay the onset of chronic disease.
Transplanting a small number of aging cells into young mice can trigger frailty and, in one study, memory loss, a new review argues, while some people born with unusually high mutation rates age completely normally.
A new historical review argues that aging is driven less by accumulated molecular damage than by growth and developmental programs that keep running past their purpose, a framework called hyperfunction that is now being tested with rejuvenation technologies.