Gladstone Institutes is an American independent, non-profit biomedical research organization whose focus is to better understand, prevent, treat and cure cardiovascular, viral and neurological conditions such as heart failure, HIV/AIDS and Alzheimer’s disease.
By systematically disabling nearly 12,000 genes across 33.4 million primary human T cells, researchers revealed how genetic networks drastically alter their behavior between resting and activated immune states.
Engineered spinal interneurons grown from human stem cells survived inside injured rats, took input from the brainstem and passed signals on to the diaphragm, though every animal needed daily immunosuppression and the gain showed only under respiratory stress.