ScholarPeer’s latest research news and reporting from Mass General Brigham. Mass General Brigham is a leading academic healthcare system and biomedical research organization, bringing together renowned hospitals, clinicians and scientists across the greater Boston area. Its researchers drive advances in areas such as cancer, neuroscience, genetics, immunology, cardiovascular medicine and artificial intelligence, with a strong emphasis on translating laboratory discoveries into new diagnostics, treatments and improvements in patient care.
In mice lacking an autism-linked gene, inhibitory neurons in the hippocampus no longer remodeled themselves after social experience. Boosting a single plasticity gene in those cells, in adult animals, rebalanced the circuit, improved memory, sharpened brain rhythms, and cut seizures from ten of fourteen mice to three of twelve.