Nature Neuroscience is a leading peer-reviewed journal publishing influential research on the brain, nervous system and the biological basis of behavior. It features studies spanning molecular and cellular neuroscience, neural circuits, cognition, development and neurological disease, with an emphasis on discoveries that significantly advance understanding of how the nervous system works.
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Mechanically squeezing an animal’s shinbone released proteins into the bloodstream that calmed neuroinflammation, cut neuron loss and nearly quadrupled survival after severe head trauma in mice.
Stanford researchers traced two separate progenitor cells in mouse embryos, one wiring up the thinking brain and the other the life support system of breathing and heartbeat, explaining why hindbrain neurons have been nearly impossible to grow in a lab.
Mice bred with tau pathology and Alzheimer’s genetics lost their brain-damaging immune response when researchers deleted a scarce class of dendritic cells that operates entirely in lymph nodes outside the brain.
In living mice, astrocytes around small brain lesions divided and sent new nuclei through their own branches to refill the emptied tissue. The nuclei moved in stop-and-go bursts, stretching as they squeezed through narrow processes. In comparable stroke lesions, the same refilling response was almost absent.